-
br Q Experiment similar to that shown in panel
2020-08-18
(Q) Experiment similar to that shown in panel P but done with 100 mM Trolox. Values are the mean of four different NSCLC cell lines and normalized to untreated controls. (legend on next page) Figure S7. Glycolysis Mediates Antioxidant- and BACH1-Induced Migration and Metastasis, Related to F
-
br The Authors Production and
2020-08-18
2019 The Authors. Production and hosting by Elsevier B.V. on behalf of King Saud University. This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/). 1. Introduction Lung cancer in men is the most common cause of death world-wide (WHO,
-
br Table br Sex br Male Prior cancer history
2020-08-18
Table 1 Sex % Male 75 Prior cancer history 9 Neo-adjuvant treatment Female 25 Chemotherapy < 1 History of psychiatric illness 11 Chemoradiation 3 Ethnicity None 96 Hispanic 4 Smoking history Non-Hispanic 75 Never smoked 41 Prophylactic PEG Placement 11 Unk
-
br Our study improves on previous
2020-08-14
Our study improves on previous studies in that we examined the interaction between a number of biologically plausible poly-morphisms in different genes that are involved in a wide range of cancer-related processes, not just SNPs in a single gene or in genes acting on a specific pathway. The observ
-
br Figure Scatterplot of Postsurgical
2020-08-14
Figure 2 Scatterplot of Postsurgical Cancer of the Prostate Risk Assessment (CAPRA-S) Scores According to Income Level for Each Individual Patient; an Inverse Association Is Shown Despite limited understanding of the mechanisms through which low SES increases the risk of adverse prostate cancer
-
br Dynamic enhanced magnetic resonance imaging comparing
2020-08-12
Dynamic enhanced magnetic resonance imaging comparing lesion TIC type results According to the TIC classification criteria of time signal inten-sity curve, before neoadjuvant chemotherapy, in 30 cases of malignant lesions, the number of type I is 0, the number of type II is 8, and the number of
-
br Table br IC concentrations g ml of the Iscucin
2020-08-12
Table 2 IC50 concentrations (μg/ml) of the Iscucin® preparations compared to Actinomycin-D from different cancer cell lines. Table 3 ML-1 contents (ng/ml) at the IC50 concentrations of the Iscucin® preparations. Ricin neuroblastoma lung cancer cervix cancer glioma renal cell ca
-
br Fig Isotherm and pore distribution curves of a
2020-08-12
Fig. 8. Isotherm and pore distribution curves of a) [email protected] and b) [email protected]@L-Dopa based on the BET and BJH method, respectively. Finally, the forth mass loss step in temperature above 570 °C is probably due to the decomposition of the mixed metal oxide into a spinel phase [33].
-
br Astragalus membranaceus has been
2020-08-12
Astragalus membranaceus, has been shown to exhibit broad-range in-hibitory effect on various types of solid tumors [5]. Previous report demonstrated APS exhibited favorable anti-melanoma potency by down-regulating CD40 expression [6]. Besides, APS exerted a sy-nergistic anti-tumor effect in combinat
-
br modulations determined by kinase abundance In
2020-08-12
modulations determined by kinase abundance. In summary, these data show that protein overexpression effects can be cat-alytic or non-catalytic and suggest that activity-based modeling of signaling network deregulation for drug target discovery alone is likely insufficient. Signaling Relationshi
-
br c Laboratory of Vaccine
2020-08-12
c Laboratory of Vaccine Materials, Center for Vaccine and Adjuvant Research, and Laboratory of Gut Environmental System, National Institutes of Biomedical Innovation, Health and Nutrition, 7-6-8 Asagi, Saito, Ibaraki-shi, Osaka, 567-0085, Japan d Department of Oral and Maxillofacial Surgery, So
-
br rate dehydrogenase PHGDH and through
2020-08-12
rate dehydrogenase (PHGDH) and through successive steps into serine. Serine is then converted by serine hy- droxymethyltransferase 2 (SHMT2) into glycine. The carbon unit is incorporated into the folate cycle which transfers the carbon unit to homocysteine to generate methionine. T
-
br The reduction of ESTAC
2020-08-12
The reduction of 7ESTAC01 showed the first cathodic peak at EIc = −0.38 V, which was lower than the 9-aminoacridine alone. This behaviour hinted a possible synergic activity of 7ESTAC01 due to the significant shift of the first cathodic peak potential. It is worth men-tioning that most of the bioa
-
br Nanoparticles can be exploited to address some of the
2020-08-07
Nanoparticles can be exploited to address some of the aforementioned challenges. To simplify the production of CAR T-cells, Stephan et al. developed T-cell-targeting nanoparticles delivering plasmid DNA specifically constructed against CD19 antigens that were ubiquitously expressed on B lineage le
-
br G Draetta P Jones
2020-08-07
G. Draetta, P. Jones, C. Toniatti, M.E.D. Francesco, J.R. Marszalek, A novel OXPHOS inhibitor which selectively kill tumors with metabolic vulnerabilities, The 106th Annual Meeting of the American Association for Cancer Research, AACR, Philadelphia, PA, 2015. Contents lists available at Science